synHSV™ is capable of delivering up to 30x the payload of AAV. We can deliver big genes, genomic genes, and multiple genes, unlocking the promise of polygenic medicine.
83% of genes are too big for AAV
Retinitis pigmentosa is a group of rare eye diseases that affect the retina. RP causes progressive disfunction of rod photoreceptors with subsequent degeneration of cone photoreceptors and the retinal pigment epithelium, resulting in vision loss. Symptoms start in childhood and most individuals eventually lose the majority of their sight.
TET and APOBEC are key enzymes in DNA methylation analysis. Methylation analysis is increasingly the approach of choice for early cancer detection (ECDx), as it has high sensitivity and provides tissue of origin information.