synHSV™ is capable of delivering up to 30x the payload of AAV. We can deliver big genes, genomic genes, and multiple genes, unlocking the promise of polygenic medicine.
83% of genes are too big for AAV
uCell™ is an immune silencing technology that enables iPSCs to be used as a renewable source for cell therapies. This substantially reduces the cost of goods associated with patient- or pooled donor-derived cells, improves product consistency and volume, and enables extensive genome engineering.
DropSynth™ enables the efficient assembly of large libraries of gene-size fragments. These can be used to explore protein sequence space in a manner that is more efficient, cost-effective, and comprehensive than directed evolution.
Writing DNA is a million times more expensive than sequencing. Reducing the cost of writing to those of reading will enable the era of genome writing, which has the potential to disrupt multiple industries.
Learned Ancestral Sequence Recognition (LASR™) is an evolutionary inference machine learning algorithm capable of converting phylogenetic tree space into DNA sequence space in order to identify fitness peaks within evolutionary landscapes. In combination with DropSynth™, this technology provides a differentiated method for the efficient navigation of protein sequence space.
LASR™ can identify global maxima (fitness peaks), located far away from the extant protein sequence.
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